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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3250
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pak1
Name: p21 (RAC1) activated kinase 1
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pak1affects expressionISOPak1 (Mus musculus)6480464CTDTamoxifen affects the expression of PAK1 mRNAPMID:17555576
Pak1affects response to substanceISOPAK1 (Homo sapiens)6480464CTDPAK1 affects the susceptibility to TamoxifenPMID:20179234
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