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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353801 Species: Homo sapiens RGD Object: Gene Symbol: PLK1 Name: polo-like kinase 1

Acc ID: CHEBI:41774 Term: tamoxifen Definition: A stilbenoid that has formula C26H29NO. CasRN: 10540-29-1 Chemical ID: MESH:D013629

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Tamoxifen inhibits the reaction [Estradiol results in increased expression of PLK1 protein]	PMID:20208560