GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | decreases response to substance | EXP | | 6480464 | CTD | chymostatin results in decreased susceptibility to AGT protein modified form | PMID:21602471 | Agt | multiple interactions | EXP | | 6480464 | CTD | Enalapril affects the reaction [chymostatin results in decreased susceptibility to AGT protein modified form] | PMID:21602471 | Agt | decreases expression | ISO | Agt (Mus musculus) | 6480464 | CTD | chymostatin results in decreased expression of AGT protein modified form | PMID:18300870 | Agt | multiple interactions | ISO | AGT (Homo sapiens) | 6480464 | CTD | [[Lisinopril co-treated with chymostatin] affects the metabolism of AGT protein] which results in decreased abundance of Angiotensin II; [Lisinopril co-treated with chymostatin] affects the metabolism of AGT protein; chymostatin inhibits the reaction [KRAS protein mutant form results in increased expression of AGT protein] | PMID:27649628 PMID:33380422 | |
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