Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2543
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Egfr
Name:	epidermal growth factor receptor

Acc ID:	CHEBI:41033
Term:	benzamidine
Definition:	A carboxamidine that is benzene carrying an amidino group.
Chemical ID:	MESH:C032157

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Egfr	decreases activity	ISO	EGFR (Homo sapiens)	6480464	CTD	benzamidine analog results in decreased activity of EGFR protein	PMID:15186837

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.