GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hspa5 | increases expression | EXP | | 6480464 | CTD | Cyclosporine results in increased expression of HSPA5 mRNA; Cyclosporine results in increased expression of HSPA5 protein | PMID:20136702 PMID:25596134 PMID:35033536 | Hspa5 | multiple interactions | EXP | | 6480464 | CTD | Melatonin promotes the reaction [Cyclosporine results in increased expression of HSPA5 protein] | PMID:20136702 | Hspa5 | increases expression | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | Cyclosporine results in increased expression of HSPA5 mRNA; Cyclosporine results in increased expression of HSPA5 protein | PMID:22155090 PMID:23308384 PMID:25047351 | Hspa5 | increases expression | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | Cyclosporine results in increased expression of HSPA5 mRNA; Cyclosporine results in increased expression of HSPA5 protein | PMID:19159671 PMID:20106945 PMID:21163907 PMID:21632981 PMID:24973091 PMID:25562108 PMID:25596134 PMID:27358234 PMID:27989131 PMID:32152650 PMID:34681664 PMID:35033536 | Hspa5 | multiple interactions | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Cyclosporine results in increased expression of HSPA5 protein] | PMID:22155090 | Hspa5 | multiple interactions | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of HSPA5 mRNA | PMID:32152650 | |
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