GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos1 | decreases activity | EXP | | 6480464 | CTD | 7-nitroindazole results in decreased activity of NOS1 protein | PMID:15556163 PMID:20633543 | Nos1 | multiple interactions | EXP | | 6480464 | CTD | 7-nitroindazole inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein]; 7-nitroindazole inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] | PMID:15245872 | Nos1 | decreases activity | ISO | Nos1 (Mus musculus) | 6480464 | CTD | 7-nitroindazole results in decreased activity of NOS1 protein | PMID:15686955 PMID:17854383 PMID:9495865 | Nos1 | multiple interactions | ISO | Nos1 (Mus musculus) | 6480464 | CTD | 7-nitroindazole inhibits the reaction [[Enoxacin co-treated with fenbufen] results in increased activity of NOS1 protein]; 7-nitroindazole inhibits the reaction [[N-isopropylbenzylamine results in increased expression of NOS1 protein] which results in increased abundance of Nitric Oxide]; [7-nitroindazole results in decreased activity of NOS1 protein] inhibits the reaction [[Morphine co-treated with Naloxone] results in increased activity of MMP9 protein]; [7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which results in decreased susceptibility to Methamphetamine | PMID:11006970 PMID:17426488 PMID:20519536 PMID:36162621 PMID:8858965 PMID:9495865 PMID:9623721 | | ||||||||||||||||||||||
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