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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: CHEBI:40071
Term: 4-amino-1,8-naphthalimide
Definition: A benzoisoquinoline that has formula C12H8N2O2.
Chemical ID: MESH:C086538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chek2increases phosphorylationISOChek2 (Mus musculus)6480464CTD4-amino-1,8-naphthalimide results in increased phosphorylation of CHEK2 proteinPMID:16556909
Chek2multiple interactionsISOChek2 (Mus musculus)6480464CTDPARP1 protein affects the reaction [4-amino-1,8-naphthalimide results in increased phosphorylation of CHEK2 protein]PMID:16556909
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