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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708376
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psmc5
Name: proteasome 26S subunit, ATPase 5
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmc5increases expressionEXP 6480464CTDValproic Acid results in increased expression of PSMC5 mRNAPMID:21318169
Psmc5decreases methylationISOPSMC5 (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of PSMC5 genePMID:29154799
Psmc5increases expressionISOPSMC5 (Homo sapiens)6480464CTDValproic Acid results in increased expression of PSMC5 mRNAPMID:23179753
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