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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631409
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90aa1
Name: heat shock protein 90 alpha family class A member 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90aa1decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of HSP90AA1 mRNAPMID:17381134
Hsp90aa1increases expressionEXP 6480464CTDValproic Acid results in increased expression of HSP90AA1 mRNAPMID:21318169
Hsp90aa1affects expressionISOHsp90aa1 (Mus musculus)6480464CTDValproic Acid affects the expression of HSP90AA1 mRNAPMID:17292431
Hsp90aa1decreases expressionISOHSP90AA1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of HSP90AA1 mRNAPMID:23179753
Hsp90aa1increases methylationISOHSP90AA1 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of HSP90AA1 genePMID:29154799
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