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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628710 Species: Rattus norvegicus RGD Object: Gene Symbol: Nalcn Name: sodium leak channel, non-selective

Acc ID: CHEBI:39867 Term: valproic acid Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. CasRN: 99-66-1 Chemical ID: MESH:D014635

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:733715	6480464	CTD	[Hydralazine co-treated with Valproic Acid] results in increased expression of NALCN mRNA	PMID:17183730