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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pdincreases expressionEXP 6480464CTDValproic Acid results in increased expression of G6PDX mRNAPMID:19224547
G6pdaffects expressionISOG6PD (Homo sapiens)6480464CTDValproic Acid affects the expression of G6PD mRNAPMID:25979313
G6pdincreases expressionISOG6PD (Homo sapiens)6480464CTDValproic Acid results in increased expression of G6PD mRNAPMID:25399406 PMID:29154799
G6pdincreases methylationISOG6PD (Homo sapiens)6480464CTDValproic Acid results in increased methylation of G6PD genePMID:29154799
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