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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315043 Species: Homo sapiens RGD Object: Gene Symbol: MAP3K5 Name: mitogen-activated protein kinase kinase kinase 5

Acc ID: CHEBI:39867 Term: valproic acid Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. CasRN: 99-66-1 Chemical ID: MESH:D014635

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO		6480464	CTD	Valproic Acid affects the expression of MAP3K5 mRNA	PMID:17292431
affects expression	ISO	RGD:1315044	6480464	CTD	Valproic Acid affects the expression of MAP3K5 mRNA	PMID:17292431