GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sirt1 | affects expression | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | Valproic Acid affects the expression of SIRT1 mRNA | PMID:25979313 | Sirt1 | decreases expression | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in decreased expression of SIRT1 mRNA | PMID:23179753 PMID:27188386 | Sirt1 | decreases expression | ISO | Sirt1 (Mus musculus) | 6480464 | CTD | Valproic Acid results in decreased expression of SIRT1 mRNA | PMID:15799026 PMID:19136453 | Sirt1 | decreases methylation | ISO | SIRT1 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in decreased methylation of SIRT1 gene | PMID:28853863 PMID:29201983 | |
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