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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2261
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Camk2a
Name: calcium/calmodulin-dependent protein kinase II alpha
Acc ID: CHEBI:3962
Term: curcumin
Definition: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
Chemical ID: MESH:D003474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Camk2amultiple interactionsEXP 6480464CTDCurcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CAMK2A protein]PMID:29723552
Camk2amultiple interactionsISOCamk2a (Mus musculus)6480464CTD[Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of CAMK2A mRNAPMID:22911773
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