GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ahr | affects binding | ISO | Ahr (Mus musculus) | 6480464 | CTD | Curcumin binds to AHR protein | PMID:17880909 | Ahr | increases degradation | ISO | AHR (Homo sapiens) | 6480464 | CTD | Curcumin results in increased degradation of AHR protein | PMID:19018768 | Ahr | multiple interactions | ISO | Ahr (Mus musculus) | 6480464 | CTD | [Curcumin co-treated with resveratrol] inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; Curcumin inhibits the reaction [Benzo(a)pyrene affects the localization of AHR protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of AHR protein]; Curcumin inhibits the reaction [Methylcholanthrene binds to AHR protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [AHR protein co-treated with ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AHR protein]; Curcumin promotes the reaction [Tetrachlorodibenzodioxin results in increased localization of AHR protein] | PMID:17880909 PMID:18321868 PMID:25632966 | Ahr | multiple interactions | ISO | AHR (Homo sapiens) | 6480464 | CTD | AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein] | PMID:17077187 | | ||||||||||||||||||||||
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