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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620298
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg5
Name: ATP binding cassette subfamily G member 5
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg5increases expressionEXP 6480464CTDperfluorooctane sulfonic acid results in increased expression of ABCG5 mRNAPMID:21723365
Abcg5decreases expressionISOABCG5 (Homo sapiens)6480464CTDperfluorooctane sulfonic acid results in decreased expression of ABCG5 mRNAPMID:27153767 PMID:32253466
Abcg5decreases expressionISOAbcg5 (Mus musculus)6480464CTDperfluorooctane sulfonic acid results in decreased expression of ABCG5 mRNAPMID:21705711
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