GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bdnf | decreases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased expression of BDNF protein | PMID:25524167 | Bdnf | increases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of BDNF mRNA; perfluorooctane sulfonic acid results in increased expression of BDNF protein | PMID:21436126 PMID:25524167 | Bdnf | multiple interactions | EXP | | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF mRNA]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF protein]; 2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF mRNA]; 2,2',4,4'-tetrabromodiphenyl ether promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BDNF protein]; [2,2',4,4'-tetrabromodiphenyl ether co-treated with perfluorooctane sulfonic acid] results in increased expression of BDNF protein | PMID:21436126 | Bdnf | multiple interactions | ISO | Bdnf (Mus musculus) | 6480464 | CTD | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of BDNF mRNA | PMID:36331819 | |
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