GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | decreases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA; perfluorooctane sulfonic acid results in decreased expression of BCL2 protein | PMID:24616003 PMID:26844784 PMID:35934180 | Bcl2 | increases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of BCL2 protein | PMID:31588057 | Bcl2 | decreases expression | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA; perfluorooctane sulfonic acid results in decreased expression of BCL2 protein | PMID:21115943 PMID:23562911 PMID:34303733 PMID:36988283 | Bcl2 | decreases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA; perfluorooctane sulfonic acid results in decreased expression of BCL2 protein | PMID:19468714 PMID:22976841 PMID:26844784 PMID:34006824 PMID:36988283 | Bcl2 | increases expression | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of BCL2 mRNA | PMID:23562911 | Bcl2 | multiple interactions | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 protein] | PMID:36988283 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 protein]; MIR155 mRNA promotes the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 protein] | PMID:22976841 PMID:26844784 PMID:36988283 | |
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