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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:39214
Term: abamectin
Definition: Mixture of 80% avermectin B1a and 20% avermectin B1b.
Chemical ID: MESH:C048324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1decreases activityISOABCC1 (Homo sapiens)6480464CTDabamectin results in decreased activity of ABCC1 proteinPMID:25865432
Abcc1multiple interactionsISOAbcc1 (Mus musculus)6480464CTDabamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]PMID:25865432
Abcc1multiple interactionsISOABCC1 (Homo sapiens)6480464CTDabamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]PMID:25865432
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