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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:3908
Term: coumestrol
Definition: A member of the class of coumestans that is coumestan with hydroxy substituents at positions 3 and 9.
Chemical ID: MESH:D003375
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ardecreases expressionISOAR (Homo sapiens)6480464CTDCoumestrol results in decreased expression of AR mRNAPMID:11867264
Armultiple interactionsISOAR (Homo sapiens)6480464CTDCoumestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]PMID:29162470
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