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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2845
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Htr1a
Name: 5-hydroxytryptamine receptor 1A
Acc ID: CHEBI:38721
Term: methamidophos
Definition: An organic thiophosphate resulting from the N-deacylation of the proinsecticide acephate.
Chemical ID: MESH:C014655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Htr1aaffects activityISOHtr1a (Mus musculus)6480464CTDmethamidophos affects the activity of HTR1A proteinPMID:23596261
Htr1amultiple interactionsISOHtr1a (Mus musculus)6480464CTDmethamidophos inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]PMID:21871486
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