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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3731 Species: Rattus norvegicus RGD Object: Gene Symbol: Sod1 Name: superoxide dismutase 1, soluble

Acc ID: CHEBI:38545 Term: rosuvastatin Definition: A pyrimidine that has formula C22H28FN3O6S. CasRN: 287714-41-4 Chemical ID: MESH:C422923

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[[[rosuvastatin results in decreased expression of CYBB] co-treated with [rosuvastatin results in decreased expression of CYBA]] co-treated with [rosuvastatin results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species	PMID:21562509
increases expression	EXP		6480464	CTD	rosuvastatin results in increased expression of SOD1	PMID:21562509