Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621805
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b3
Name: hydroxysteroid (17-beta) dehydrogenase 3
Acc ID: CHEBI:38397
Term: perfluorononanoic acid
Definition: A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines.
Chemical ID: MESH:C101816
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b3multiple interactionsEXP 6480464CTD[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD17B3 mRNAPMID:25588985
Hsd17b3decreases expressionISOHsd17b3 (Mus musculus)6480464CTDperfluoro-n-nonanoic acid results in decreased expression of HSD17B3 mRNA; perfluoro-n-nonanoic acid results in decreased expression of HSD17B3 proteinPMID:30294798
Go Back to source page   Continue to Ontology report