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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552739 Species: Mus musculus RGD Object: Gene Symbol: Vta1 Name: Vps20-associated 1 homolog (S. cerevisiae)

Acc ID: CHEBI:379896 Term: 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one Definition: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. CasRN: 965-93-5 Chemical ID: MESH:D015741

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1312819	6480464	CTD	Metribolone results in decreased expression of VTA1 protein	PMID:17152098