GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Htr2c | affects binding | EXP | | 6480464 | CTD | Clozapine binds to HTR2C protein | PMID:9723970 | Htr2c | decreases expression | EXP | | 6480464 | CTD | Clozapine results in decreased expression of HTR2C mRNA | PMID:17868938 | Htr2c | affects binding | ISO | HTR2C (Homo sapiens) | 6480464 | CTD | Clozapine binds to HTR2C protein | PMID:16983399 | Htr2c | affects response to substance | ISO | HTR2C (Homo sapiens) | 6480464 | CTD | HTR2C gene polymorphism affects the susceptibility to Clozapine; HTR2C gene SNP affects the susceptibility to Clozapine; HTR2C promoter SNP affects the susceptibility to Clozapine; HTR2C protein affects the susceptibility to Clozapine | PMID:12668355 PMID:15635667 PMID:19142101 PMID:19142110 | |
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