GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmgcr | increases activity | ISO | HMGCR (Homo sapiens) | 6480464 | CTD | Clozapine results in increased activity of HMGCR protein | PMID:16027736 | Hmgcr | increases expression | ISO | HMGCR (Homo sapiens) | 6480464 | CTD | Clozapine results in increased expression of HMGCR mRNA | PMID:16027736 PMID:17052361 | Hmgcr | multiple interactions | ISO | HMGCR (Homo sapiens) | 6480464 | CTD | [Clozapine results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Clozapine results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides | PMID:16027736 | |
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