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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:3764
Term: clotrimazole
Definition: A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.
Chemical ID: MESH:D003022
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasmultiple interactionsISOFas (Mus musculus)6480464CTD[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of and results in increased activity of FAS protein]PMID:22033380
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