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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Acc ID: CHEBI:3764
Term: clotrimazole
Definition: A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.
Chemical ID: MESH:D003022
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpm2multiple interactionsEXP 6480464CTDClotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]PMID:21900507
Trpm2multiple interactionsISOTRPM2 (Homo sapiens)6480464CTD[Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]PMID:22036725
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