GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | increases expression | EXP | | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA | PMID:7564102 | Sod2 | increases abundance | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species] which results in increased abundance of SOD2 | PMID:21705328 | Sod2 | increases activity | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein | PMID:12161520 | Sod2 | increases expression | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein | PMID:9756418 | Sod2 | increases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | [Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein | PMID:10601319 PMID:10669635 PMID:10769695 PMID:12161520 PMID:15330761 PMID:17309078 PMID:20831825 PMID:21705328 PMID:8037686 PMID:9434740 PMID:9837861 PMID:9852137 | Sod2 | multiple interactions | ISO | Sod2 (Mus musculus) | 6480464 | CTD | [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD2 protein; SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] | PMID:11507057 PMID:31351099 PMID:9067545 | Sod2 | multiple interactions | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOD2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin]; Tetradecanoylphorbol Acetate inhibits the reaction [12-deoxyphorbolphenylacetate-20-acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [thymeleatoxin results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of SOD2 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of SOD2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA] | PMID:10601319 PMID:10669635 PMID:12161520 PMID:15330761 PMID:17309078 PMID:18958680 PMID:21045076 PMID:21705328 PMID:22429591 PMID:8037686 PMID:8702551 PMID:9852137 | |
Go Back to source page | Continue to Ontology report |