GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egfr | increases expression | EXP | | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA | PMID:10516208 | Egfr | increases expression | ISO | Egfr (Mus musculus) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased expression of EGFR | PMID:26100520 | Egfr | increases expression | ISO | EGFR (Homo sapiens) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased expression of EGFR protein | PMID:19447859 PMID:25866363 | Egfr | increases phosphorylation | ISO | Egfr (Mus musculus) | 6480464 | CTD | Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein | PMID:26513295 | Egfr | multiple interactions | ISO | Egfr (Mus musculus) | 6480464 | CTD | [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] | PMID:20660715 PMID:26100520 PMID:6309801 | Egfr | multiple interactions | ISO | EGFR (Homo sapiens) | 6480464 | CTD | naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] | PMID:19447859 PMID:25866363 | | ||||||||||||||||||||||
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