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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acaa1a
Name: acetyl-CoA acyltransferase 1A
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acaa1aincreases expressionEXP 6480464CTDClofibrate results in increased expression of ACAA1A mRNAPMID:12851107 PMID:15033592 PMID:32741897
Acaa1aincreases expressionISOAcaa1a (Mus musculus)6480464CTDClofibrate results in increased expression of ACAA1A mRNAPMID:17585979 PMID:23811191 PMID:30629241
Acaa1amultiple interactionsISOAcaa1a (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of ACAA1A mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ACAA1A mRNA]PMID:17585979
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