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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2235 Species: Rattus norvegicus RGD Object: Gene Symbol: C4bpa Name: complement component 4 binding protein, alpha

Acc ID: CHEBI:3750 Term: clofibrate Definition: A propanoate ester that has formula C12H15ClO3. CasRN: 637-07-0 Chemical ID: MESH:D002994

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:10258	6480464	CTD	[Clofibrate co-treated with Acetaminophen] affects the expression of C4BP mRNA PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of C4BP mRNA]	PMID:17585979
decreases expression	ISO	RGD:10258	6480464	CTD	Clofibrate results in decreased expression of C4BP mRNA	PMID:17585979
affects expression	EXP		6480464	CTD	Clofibrate affects the expression of C4BPA mRNA	PMID:19483382