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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2050
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adora2b
Name: adenosine A2B receptor
Acc ID: CHEBI:37325
Term: alloxazine
Definition: A benzo[g]pteridine-2,4-dione that has formula C10H6N4O2.
Chemical ID: MESH:C008173
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adora2bmultiple interactionsEXP 6480464CTD[isoalloxazine binds to and results in decreased activity of ADORA2B protein] which results in decreased susceptibility to alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; isoalloxazine binds to and results in decreased activity of ADORA2B protein; isoalloxazine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in increased activity of ADORA2B protein]PMID:16601261
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