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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621638
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adh7
Name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Acc ID: CHEBI:3699
Term: cimetidine
Definition: A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Chemical ID: MESH:D002927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adh7multiple interactionsISOADH7 (Homo sapiens)6480464CTDCimetidine inhibits the reaction [ADH7 protein results in increased oxidation of Ethanol]PMID:23220590
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