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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:36904
Term: elemental selenium
Definition: null
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTDSelenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]PMID:34612572
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDSelenium results in decreased expression of BCL2 proteinPMID:17523932
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]PMID:27920530 PMID:34612572
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