GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Alox5 | increases expression | ISO | ALOX5 (Homo sapiens) | 6480464 | CTD | Platelet Activating Factor results in increased expression of ALOX5 mRNA | PMID:16386258 | Alox5 | multiple interactions | ISO | ALOX5 (Homo sapiens) | 6480464 | CTD | [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein; [zileuton results in decreased activity of ALOX5 protein] inhibits the reaction [Calcimycin results in increased abundance of Platelet Activating Factor] | PMID:10779545 PMID:8387780 | |
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