GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cd86 | increases expression | ISO | Cd86 (Mus musculus) | 6480464 | CTD | Imiquimod results in increased expression of CD86 protein | PMID:22916010 PMID:31093508 | Cd86 | multiple interactions | ISO | Cd86 (Mus musculus) | 6480464 | CTD | [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of CD86 protein; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased expression of CD86 protein]; Tetrachlorodibenzodioxin promotes the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of CD86 protein] | PMID:21097750 PMID:22916010 | | ||||||||||||||||||||||
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