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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:36560
Term: zinc oxide
Definition: A zinc molecular entity that has formula OZn.
Chemical ID: MESH:D015034
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasdecreases expressionISOFAS (Homo sapiens)6480464CTDZinc Oxide results in decreased expression of FAS mRNAPMID:32600046
Fasincreases expressionISOFAS (Homo sapiens)6480464CTDZinc Oxide analog results in increased expression of FAS proteinPMID:27544635
Fasmultiple interactionsISOFAS (Homo sapiens)6480464CTDbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Zinc Oxide analog results in increased expression of FAS protein]; Thioctic Acid inhibits the reaction [Zinc Oxide analog results in increased expression of FAS protein]PMID:27544635
Fasmultiple interactionsISOFas (Mus musculus)6480464CTDZinc Oxide affects the splicing of and results in increased expression of FAS mRNAPMID:30500950
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