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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344997 Species: Homo sapiens RGD Object: Gene Symbol: SULT2A1 Name: sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1

Acc ID: CHEBI:36090 Term: 4-coumaric acid Definition: A monohydroxycinnamic acid in which the hydroxy substituent is located at C-4 of the phenyl ring. CasRN: 7400-08-0 Chemical ID: MESH:C032171

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases activity	ISO	RGD:621337	6480464	CTD	4-coumaric acid results in increased activity of SULT2A1 protein	PMID:16443358
increases expression	ISO	RGD:621337	6480464	CTD	4-coumaric acid results in increased expression of SULT2A1 mRNA	PMID:16443358