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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736042 Species: Homo sapiens RGD Object: Gene Symbol: IGFBP3 Name: insulin-like growth factor binding protein 3

Acc ID: CHEBI:35807 Term: N-nitrosodimethylamine Definition: A nitrosamine that has formula C2H6N2O. CasRN: 62-75-9 Chemical ID: MESH:D004128

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:2874	6480464	CTD	Dimethylnitrosamine results in decreased expression of IGFBP3 mRNA	PMID:15890375