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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3733
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod3
Name: superoxide dismutase 3
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod3decreases expressionEXP 6480464CTDcobaltous chloride results in decreased expression of SOD3 mRNAPMID:21804221 PMID:24386269
Sod3multiple interactionsEXP 6480464CTD4-phenylbutyric acid inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA]PMID:21804221
Sod3decreases expressionISOSod3 (Mus musculus)6480464CTDcobaltous chloride results in decreased expression of SOD3 mRNAPMID:20594416
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