GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | multiple interactions | EXP | | 6480464 | CTD | cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased expression of CCL2 protein] | PMID:18635243 PMID:19278353 PMID:21296072 | Ccl2 | decreases expression | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in decreased expression of CCL2 mRNA | PMID:14652683 PMID:19376846 | Ccl2 | increases expression | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | cobaltous chloride results in increased expression of CCL2 mRNA | PMID:23684559 PMID:25966675 | Ccl2 | increases response to substance | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | CCL2 results in increased susceptibility to cobaltous chloride | PMID:23043544 | Ccl2 | increases secretion | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased secretion of CCL2 protein | PMID:21110705 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with chromic chloride] results in increased expression of CCL2 mRNA; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of CCL2 mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of CCL2 mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA | PMID:25966675 PMID:32408695 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased expression of and results in increased secretion of CCL2 protein | PMID:23629852 | |
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