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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708392
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a9
Name: cytochrome P450, family 3, subfamily a, polypeptide 9
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a9affects expressionISOCyp3a13 (Mus musculus)6480464CTDperfluorooctanoic acid affects the expression of CYP3A13 mRNAPMID:18281256
Cyp3a9increases expressionISOCYP3A5 (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of CYP3A5 mRNAPMID:37302725
Cyp3a9increases expressionISOCyp3a13 (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of CYP3A13 mRNAPMID:25949234
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