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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620007
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2j4
Name: cytochrome P450, family 2, subfamily j, polypeptide 4
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2j4increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of CYP2J4 mRNAPMID:16221955 PMID:28511854
Cyp2j4increases expressionISOCYP2J2 (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of CYP2J2 mRNAPMID:32588087
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