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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620266
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc4
Name: ATP binding cassette subfamily C member 4
Acc ID: CHEBI:35546
Term: perfluorodecanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated decanoic acid.
Chemical ID: MESH:C036567
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc4increases expressionISOAbcc4 (Mus musculus)6480464CTDperfluorodecanoic acid results in increased expression of ABCC4 mRNAPMID:18757529 PMID:27344344
Abcc4multiple interactionsISOAbcc4 (Mus musculus)6480464CTDgadolinium chloride inhibits the reaction [perfluorodecanoic acid results in increased expression of ABCC4 mRNA]; NFE2L2 protein affects the reaction [perfluorodecanoic acid results in increased expression of ABCC4 mRNA]; PPARA protein affects the reaction [perfluorodecanoic acid results in increased expression of ABCC4 mRNA]PMID:18757529
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