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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3177
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ngfr
Name: nerve growth factor receptor
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ngfrincreases expressionISONGFR (Homo sapiens)6480464CTDCadmium Chloride results in increased expression of NGFR proteinPMID:21796402
Ngfrmultiple interactionsISONgfr (Mus musculus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NGFR mRNAPMID:36114956
Ngfrmultiple interactionsISONGFR (Homo sapiens)6480464CTDNGFR protein affects the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]PMID:21796402
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