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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309424 Species: Rattus norvegicus RGD Object: Gene Symbol: Ncf2 Name: neutrophil cytosolic factor 2

Acc ID: CHEBI:35456 Term: cadmium dichloride Definition: A cadmium coordination entity that has formula CdCl2. CasRN: 10108-64-2 Chemical ID: MESH:D019256

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1319760	6480464	CTD	Cadmium Chloride results in increased expression of NCF2 protein	PMID:21195169
multiple interactions	EXP		6480464	CTD	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] PTEN inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein] Sirolimus inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein]	PMID:21195169
increases expression	EXP		6480464	CTD	Cadmium Chloride results in increased expression of NCF2 protein	PMID:21195169