Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305769
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pink1
Name: PTEN induced kinase 1
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pink1decreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of PINK1 mRNAPMID:33453195
Pink1increases expressionEXP 6480464CTDCadmium Chloride results in increased expression of PINK1 proteinPMID:37451666
Pink1multiple interactionsEXP 6480464CTDSIRT1 protein inhibits the reaction [Cadmium Chloride results in increased expression of PINK1 protein]PMID:37451666
Pink1increases expressionISOPink1 (Mus musculus)6480464CTDCadmium Chloride results in increased expression of PINK1 mRNAPMID:20883709
Pink1multiple interactionsISOPink1 (Mus musculus)6480464CTD3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PINK1 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PINK1 protein; PINK1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKN protein]; PINK1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SQSTM1 protein]; PINK1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased lipidation of MAP1LC3B protein]PMID:34952138 PMID:37022104
Go Back to source page   Continue to Ontology report