GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pink1 | decreases expression | EXP | | 6480464 | CTD | Cadmium Chloride results in decreased expression of PINK1 mRNA | PMID:33453195 | Pink1 | increases expression | EXP | | 6480464 | CTD | Cadmium Chloride results in increased expression of PINK1 protein | PMID:37451666 | Pink1 | multiple interactions | EXP | | 6480464 | CTD | SIRT1 protein inhibits the reaction [Cadmium Chloride results in increased expression of PINK1 protein] | PMID:37451666 | Pink1 | increases expression | ISO | Pink1 (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in increased expression of PINK1 mRNA | PMID:20883709 | Pink1 | multiple interactions | ISO | Pink1 (Mus musculus) | 6480464 | CTD | 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PINK1 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PINK1 protein; PINK1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKN protein]; PINK1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SQSTM1 protein]; PINK1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased lipidation of MAP1LC3B protein] | PMID:34952138 PMID:37022104 | |
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