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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:35455
Term: 1-naphthyl isothiocyanate
Definition: An isothiocyanate that has formula C11H7NS.
Chemical ID: MESH:D015058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10affects expressionEXP 6480464CTD1-Naphthylisothiocyanate affects the expression of IL10 proteinPMID:25051504
Il10increases expressionISOIl10 (Mus musculus)6480464CTD1-Naphthylisothiocyanate results in increased expression of IL10 mRNAPMID:30517764
Il10multiple interactionsISOIl10 (Mus musculus)6480464CTD[PPARA protein affects the susceptibility to 1-Naphthylisothiocyanate] which affects the expression of IL10 mRNA; Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL10 mRNA]PMID:30352267 PMID:30517764
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