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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2483
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp7b1
Name: cytochrome P450 family 7 subfamily B member 1
Acc ID: CHEBI:35455
Term: 1-naphthyl isothiocyanate
Definition: An isothiocyanate that has formula C11H7NS.
Chemical ID: MESH:D015058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp7b1decreases expressionISOCyp7b1 (Mus musculus)6480464CTD1-Naphthylisothiocyanate results in decreased expression of CYP7B1 mRNAPMID:28549656 PMID:30517764
Cyp7b1multiple interactionsISOCyp7b1 (Mus musculus)6480464CTD[NR1H4 protein results in increased susceptibility to 1-Naphthylisothiocyanate] which results in decreased expression of CYP7B1 mRNAPMID:29968724
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